Gentle Collagenase Injection Protocol (GCIP)
A Safer, Controlled Approach to Treating Dupuytren’s Contracture
From the essay
The standard approach for treating Dupuytren's contracture using enzymatic injections (e.g., collagenase clostridium histolyticum) involves a high-dose injection followed by a forced extension maneuver to rupture the fibrous cord. This practice carries a high risk of complications, including skin tears, tendon injury, nerve damage, and uncontrolled enzyme diffusion.
Adapted from PDF pages 1.